Dr. Rao V. L. Papineni is an invited Chairperson and a Speaker at “Imaging Cell Therapy session” in the 18th Annual Meeting of International Society for Cellular Therapy, Seattle, USA. The session starts at 7.30 AM June 6th 2012.
For more details please visit: http://www.celltherapysociety.org/uploads/files/Annual%20Meetings/2012/Program/ISCT%202012%20Website%20Program.pdf
WOODBRIDGE, Conn., May 14 — The Beatson Institute for Cancer Research and Carestream Molecular Imaging have signed a 5-year partnership agreement to support the development of novel preclinical imaging approaches in oncology using the Carestream Albira trimodal imaging system. The Albira was purchased by the Beatson Institute with support from funds raised by researchers in SINAPSE, a medical imaging consortium involving six premier Scottish Universities. The Albira combines PET, SPECT, and CT modalities in one platform, which provides the Beatson Institute with imaging technologies to support their research into cancer cell behavior and the development of new therapeutic, diagnostic, and prognostic tools. Research at the Beatson Institute relies heavily on the use of advanced technologies, including sophisticated transgenic cancer models and advanced imaging technologies housed within the Beatson Advanced Imaging Resource (BAIR). The BAIR is a world-leading center for preclinical fluorescence molecular imaging.
With the addition of PET, SPECT, and CT capabilities and the expertise developed by SINAPSE, the BAIR will now provide PET, SPECT, and CT imaging for a variety of research groups within the Beatson Institute, the West of Scotland Cancer Center, and other collaborators. The immediate use of the Albira will be to support oncology studies centered on understanding the genetic basis of pancreatic, colon, breast, and skin cancers and their response to treatment. The Albira system provides a 3D quantitative capability to study biological processes at the tissue and cellular level and will be used in a wide variety of research studies.
Prof. Kurt Anderson, PhD, Research Professor and BAIR Director, says “the combination of PET, SPECT, and CT technologies in one instrument provides investigators at our institutions the flexibility to support research programs across many areas of cancer research such as biomarker, theragnostics, and drug development. Use of these techniques will foster greater collaboration among researchers and help us build closer ties with our clinical imaging colleagues at the West of Scotland PET center.”
The Albira system features a unique modular architecture that introduces an exclusive, patented single crystal detector and associated electronics for rapid acquisition and reconstruction of highly resolved quantitative PET and SPECT images. This approach contrasts with the pixelated crystal technology used in most current PET and SPECT systems today.
Dr. Anderson was also pleased with the ease of use of Albira software in the acquisition, reconstruction, and analysis of images. “The workflow and interface of the software has clearly been designed with the end user researcher in mind. The complete imaging process is intuitive from the beginning whether you are acquiring a simple PET image or co-registering between PET, SPECT, or CT imaging modalities.”
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About SINAPSE
SINAPSE is a consortium of six Scottish universities (Aberdeen, Dundee, Edinburgh, Glasgow, St. Andrews, and Stirling) established with funding from the Scottish Funding Council, the Chief Scientific Office and the six Universities. The main research focus is on imaging the brain, with additional interests in oncology and cardiovascular imaging. The technology focus is primarily on magnetic resonance imaging (MRI), positron emission tomography (PET), single photon emission computed tomography (SPECT), and electrophysiology (EEG). The network provides funding that has increased the number of key research staff and students within Scotland and it allows the sharing of skills and education via e-learning, seminars and other key events.
About The Beatson
The Beatson Institute for Cancer Research conducts a program of world-class science directed at understanding key aspects of cancer cell behavior, and translation of basic science results into new therapies, diagnostic, and prognostic tools aimed at improving the lives of cancer patients. The institute is core funded by Cancer Research UK, and benefits from close interaction with the University of Glasgow, including strong links to the West of Scotland Cancer Center. For more information visit www.beatson.gla.ac.uk.
About Carestream
Carestream Health is a worldwide provider of dental and medical imaging systems and healthcare IT solutions; molecular imaging systems for life science research and drug discovery/development; x-ray film and digital x-ray systems for non-destructive testing; and advanced materials for the precision films and electronics markets. Carestream Molecular Imaging, a division of Carestream, develops and markets high performance digital imaging systems for in vitro and in-vivo imaging, PET/SPECT/CT solutions, film and accessories for the life science research, specimen radiography and drug discovery/development market segments. For more information on Carestream Molecular Imaging, visit mi.carestream.com or call 1-877-747-4357, express code 7. Outside of the United States, call 1-203-786-5657.
Tuesday, June 19, 2012
8:30 am – 2:00 pm
Research Triangle Park, NC
Thursday, June 21, 2012
8:30 am – 2:00 pm
Houston, TX
Seminar Overview
Today, cutting edge non-invasive multimodal imaging technologies and strategies are indispensable in preclinical small animal research. With the introduction of advanced multimodal imaging platforms and novel probes, researchers are now able to combine data sets across imaging technologies easier and faster than ever before. This enables them to better quantify and understand the mechanisms of disease progression at the tissue and cellular level, and ultimately, advances the discovery and development of new biomarkers, drugs and therapeutics.
In this half day seminar we will explore the work of three independent research scientists from Baylor College of Medicine and Emory Univeristy who specialize in small animal research using high resolution optical/X-ray, nuclear and/or CT systems. They will discuss the role and importance of using diverse imaging modalities within their research, including fusion techniques and strategies, to simultaneously study biodistribution and efficacy of therapeutic candidates, new probe development and validation, as well as designing target-specific theragnostics and monitoring therapeutic efficacy in real time.
In addition, a presentation by scientists from Carestream Molecular Imaging will highlight recent advances in novel PET and SPECT detector technologies, multimodal in vitro and ex vivo techniques, and a new platform architecture that combines high resolution optical (luminescence, fluorescence, radioisotopic) and X-ray imaging modalities in one system, along with unprecedented system configuration flexibility.
This seminar is free, but seating is limited. Register today.
For more information, including agendas, abstracts, presenter bios and registration details:
We will be exhibiting at the Experimental Biology show at theSan DiegoConvention CenterinSan Diego,CAfrom April 22-24. Visit us at booth 316 to see our top of the line molecular imaging systems, including:
We also have two posters being presented by one of our distinguished scientists:
Thermal burn injury induced myeloperoxidase activity in murine obesity model
Inflammation/Leukocyte-Endothelium Interactions
Sunday April 22, 2012
Poster Board Number: D75
Presentation Time: 2:00 – 3:15
Induced myeloperoxidase activity in ovarian cancer mouse model
Advances in Tumor Biology
Sunday April 22, 2012
Poster Board Number: B203
Presentation Time: 11:30 AM – 1:30 PM
We’ll be live Tweeting at the show. Follow us on Twitter @carestreammi.
Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Todd A. Sasser, Sarah E. Chapman, Shengting Li, Caroline Hudson, Sean P. Orton, Justin M. Diener, Seth T. Gammon, Carlos Correcher, W. Matthew Leevy
Abstract
Obesity is associated with increased morbidity and mortality as well as reduced metrics in quality of life.1 Both environmental and genetic factors are associated with obesity, though the precise underlying mechanisms that contribute to the disease are currently being delineated.2,3 Several small animal models of obesity have been developed and are employed in a variety of studies.4 A critical component to these experiments involves the collection of regional and/or total animal fat content data under varied conditions.
Traditional experimental methods available for measuring fat content in small animal models of obesity include invasive (e.g. ex vivo measurement of fat deposits) and non-invasive (e.g. Dual Energy X-ray Absorptiometry (DEXA), or Magnetic Resonance (MR)) protocols, each of which presents relative trade-offs. Current invasive methods for measuring fat content may provide details for organ and region specific fat distribution, but sacrificing the subjects will preclude longitudinal assessments. Conversely, current non-invasive strategies provide limited details for organ and region specific fat distribution, but enable valuable longitudinal assessment. With the advent of dedicated small animal X-ray computed tomography (CT) systems and customized analytical procedures, both organ and region specific analysis of fat distribution and longitudinal profiling may be possible. Recent reports have validated the use of CT for in vivo longitudinal imaging of adiposity in living mice.5,6 Here we provide a modified method that allows for fat/total volume measurement, analysis and visualization utilizing the Carestream Molecular Imaging Albira CT system in conjunction with PMOD and Volview software packages.
Thursday, May 31, 2012
8:30 am – 2:00 pm
Four Points by Sheraton
Seminar Overview
Today, cutting edge non-invasive multimodal imaging technologies and strategies are indispensable in preclinical small animal research. With the introduction of advanced multimodal imaging platforms and novel probes, researchers are now able to combine data sets across imaging technologies easier and faster than ever before. This enables them to better quantify and understand the mechanisms of disease progression at the tissue and cellular level, and ultimately, advances the discovery and development of new biomarkers, drugs and therapeutics.
In this half day seminar we will explore the work of three independent research scientists from Baylor, Notre Dame and Thomas Jefferson Universities who specialize in small animal research using high resolution optical/X-ray, nuclear and/or CT systems. They will discuss the role and importance of using diverse imaging modalities within their research, including fusion techniques and strategies, to simultaneously study biodistribution and efficacy of therapeutic candidates, new probe development and validation, as well as designing target-specific theragnostics and monitoring therapeutic efficacy in real time.
In addition, a presentation by scientists from Carestream Molecular Imaging will highlight recent advances in novel PET and SPECT detector technologies, multimodal in vitro and ex vivo techniques, and a new platform architecture that combines high resolution optical (luminescence, fluorescence, radioisotopic) and X-ray imaging modalities in one system, along with unprecedented system configuration flexibility.
This seminar is free, but seating is limited. Register today.
Click here for more information, including agendas, abstracts, presenter bios and registration details.
Wednesday, May 30, 2012
8:30 am – 2:00 pm
Hyatt Regency Bethesda
Seminar Overview
Today, cutting edge non-invasive multimodal imaging technologies and strategies are indispensable in preclinical small animal research. With the introduction of advanced multimodal imaging platforms and novel probes, researchers are now able to combine data sets across imaging technologies easier and faster than ever before. This enables them to better quantify and understand the mechanisms of disease progression at the tissue and cellular level, and ultimately, advances the discovery and development of new biomarkers, drugs and therapeutics.
In this half day seminar we will explore the work of two independent research scientists from Baylor and Notre Dame Universities who specialize in small animal research using high resolution optical/X-ray, nuclear and/or CT systems. They will discuss the role and importance of using diverse imaging modalities within their research, including fusion techniques and strategies, to simultaneously study biodistribution and efficacy of therapeutic candidates, new probe development and validation, as well as designing target-specific theragnostics and monitoring therapeutic efficacy in real time.
In addition, a presentation by scientists from Carestream Molecular Imaging will highlight recent advances in novel PET and SPECT detector technologies, multimodal in vitro and ex vivo techniques, and a new platform architecture that combines high resolution optical (luminescence, fluorescence, radioisotopic) and X-ray imaging modalities in one system, along with unprecedented system configuration flexibility.
This seminar is free, but seating is limited. Register today.
Click here for more information, including agendas, abstracts, presenter bios and registration details.
We will be exhibiting at the American Association for Cancer Research at the McCormick Place West in Chicago, IL from April 1 – 4. Visit us at booth 4447 to see our top of the line molecular imaging systems, including:
We also have two posters being presented by one of our distinguished scientists:
Tuesday Apr 3, 2012 1:00 PM – 5:00 PM, Section 14, Tumor Biology 39
In Vivo Imaging of Early Inflammation Response in Bacterial Infection
Wednesday Apr 4, 2012 8:00 AM – 12:00 PM, Section 15, Tumor Biology 49
Non Invasive Determination of In Vivo Myeloperoxidase Activity in Ovarian Cancer Mouse Model
We’ll be live Tweeting at the show. Follow us on Twitter @carestreammi.
Date: March 27, 2012
Time: 1:00pm EDT
Abstract: Researchers are continually developing new techniques for delivering novel therapeutic compounds as well as novel methods for delivering established chemotherapeutics. Typically researchers are interested in either more effective delivery to target sites, or they want to more specifically target cells for improved efficacy and reduced side effects. Examples of how imaging can aid in the rapid assessment of these novel targeting strategies by allowing researchers to quickly study the in vivo biodistribution of labeled compounds, nanoparticles, peptides, and micelles will be illustrated.
Who Should Attend?:
Researchers interested in learning how multi-modal imaging can be used to rapidly evaluate new drug delivery vehicles
What Will You Learn?
Workshop on Small Animal Imaging
March 15th – 16th 2012
Universityof Rijeka, Faculty of Medicine
Department of Histology & Embryology
Workshop Program
______________________________________________________________
Day 1 Thursday, March 15th
10.00 – 10.15 Dr Felix Wensveen
Welcome
10.15 – 11.00 Dr Jens Waldeck
Introduction into Molecular Imaging: A general overview and a deeper insight into optical imaging
11.00 – 11.15 Coffee break
11.15 – 12.00 Dr Stephan Halle
Visualization of CD8 T cell immunity by 2-Photon microscopy
12.00 – 13.00 Lunch ___________________________________________________________________
13.15 – 17.00 Practical Part Day 1
- In vivo imaging of melanoma in mouse models
- In vivo imaging of human astrocytoma in mouse models
- An introduction to data analysis and tumor burden quantification of in vivo images
_____________________________________________________
Day 2 Friday, March 16th
09.00 – 10.00 Dr Anna Yudina
Temperature-controlled Ultrasound-mediated intracellular delivery of cell-impermeable molecules and their in vivo tracking via optical imaging
10.00 – 11.00 Dr Ralf Bergmann
Optical imaging in small animal physiology and pharmaceutical research
11.00 – 11.15 Coffee break
11.15 – 12.15 Dr Carsten Hoeltke
Fluorescent Probes for the Optical Molecular Imaging of Vascular Pathologies
12.30 – 13.30 Lunch
______________________________________________________________
13.30 – 17.00 Practical Part Day 2
- Multi-color In vivo imaging of tumors in mouse models
- In vivo imaging of viral infection in immune-competent and immune-deficient hosts
- Data analysis, tumor burden and viral load quantification of in vivo images
